Epidemiology of acne in the general population: the risk of smoking

The study authors: T. Schäfer, A. Nienhaus, D. Vieluf, J. Berger, J. Ring.

Department of Dermatology and Allergy, Technical University of Munich, Biedersteiner Straße 29, 80802 Munich, Germany, Institute of Mathematics and Computer Science in Medicine, Universitätsklinikum Hamburg-Eppendorf, University of Hamburg, Martinistraße 52, 20246 Hamburg, Germany, Fachklinikum Borkum (Zentrum für Dermatologie, Allergologie, Pädiatrie und Umweltmedizin), Jann-Berghaus-Straße 49, 26757 Borkum, Germany

Epidemiology of acne in the general population: the risk of smoking

Acne is a common skin disorder, but epidemiological data from the general population obtained by examination are scarce. Clinical experience suggests an association between smoking and acne, although confirmatory evidence from appropriate studies is lacking.

Objectives

To determine the prevalence and demographic factors of acne in a general population sample and to investigate the association of smoking and acne on a qualitative and quantitative level.

Methods

In a cross-sectional study, 896 citizens (aged 1–87 years, median 42) of the City of Hamburg were dermatologically examined. The prevalence and severity of acne were recorded and further information on demographic variables, medical history, and alcohol and cigarette consumption were obtained by a standardized interview.

Results

According to the clinical examination, acne was present in 26·8% overall, and was more prevalent in men (29·9%) than women (23·7%) (odds ratio, OR 1·37, 95% confidence interval, CI 1·01–1·87). Prevalence followed a significant linear trend over age with peak prevalence between 14 and 29 years (P < 0·001). The reported age at onset was significantly lower in women than men (P = 0·015). According to multiple logistic regression analyses acne prevalence was significantly higher in active smokers (40·8%, OR 2·04, 95% CI 1·40–2·99) as compared with non-smokers (25·2%). A significant linear relationship between acne prevalence and number of cigarettes smoked daily was obtained (trend test: P < 0·0001). In addition, a significant dose-dependent relationship between acne severity and daily cigarette consumption was shown by linear regression analysis (P = 0·001).

Conclusions

Smoking is a clinically important contributory factor to acne prevalence and severity.

Acne is best assessed by a dermatological examination, but standardized and validated diagnostic criteria are not available. From several epidemiological studies in school children we know that almost ever ybody is affected during puberty. However, data based on a general population sample and including an actual dermatological examination are scarce. Little is known about the influence of life-style factors such as smoking on acne, although clinical experience suggests an association. We aimed to determine the prevalence and demographic factors of acne in a general population sample by a dermatological examination, and to investigate the association of smoking and acne on a qualitative and quantitative level.


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The original text taken from a:

http://www.ncbi.nlm.nih.gov/pubmed/11453915

Epidemiology of acne in the general population: the risk of smoking, T. Schäfer, A. Nienhaus, D. Vieluf, J. Berger, J. Ring, British Journal of Dermatology, Volume 145, Issue 1 July 2001 Pages 100–104