Cytisine – renaissance of well known alkaloid. Pharmacological aspects of efficacy in the treatment of tobacco dependence.

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Cytyzyna – renesans znanego alkaloidu. Aspekty farmakologiczne zastosowania w leczeniu uzależnienia od nikotyny

The study authors: PIOTR TUTKA, KATARZYNA MRÓZ WITOLD ZATOŃSKI.

Katedra i Zakład Farmakologii i Toksykologii Akademii Medycznej w Lublinie, Zakład Epidemiologii i Prewencji Nowotworów, Centrum Onkologii – Instytut im. Marii Curie Skłodowskiej w Warszawie

The results of research on "Cytisine – renaissance of well known alkaloid. Pharmacological aspects of efficacy in the treatment of tobacco dependence." conducted by PIOTR TUTKA, KATARZYNA MRÓZ WITOLD ZATOŃSKI (Cytyzyna – renesans znanego alkaloidu. Aspekty farmakologiczne zastosowania w leczeniu uzależnienia od nikotyny, PIOTR TUTKA, KATARZYNA MRÓZ WITOLD ZATOŃSKI,FARMAKOTERAPIA W PSYCHIATRII I NEUROLOGII, 2006, 1, 33–39).

Cytisine – renaissance of well known alkaloid. Pharmacological aspects of efficacy in the treatment of tobacco dependence

Cytisine is an alkaloid of plant origin known in the health service for over fifty years, having agonistic properties to cholinergic nicotinic receptors. In the recent years, a few interesting results of studies on cytisine that aroused scientists and physicans interest in the drug have been published.

The first part of the paper describes the new data, particulary concerning the pharmacodynamics of cytisine, which constitutes a strong indication to the treatment of nicotine addiction and maybe other disorders and diseases. In the further part of the paper the most characteristic results of central and peripheral action of cytisine are discussed. The initial results of clinical studies confirm the ef- ficacy of cytisine comparable with the efficacy of bupropion, the drug used as first-line pharmacotherapy for tobacco dependence. Attention is drawn to cytisine as a paternal substance to the search for other effective therapeutically and safe analogues.

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The complete study "Cytisine – renaissance of well known alkaloid. Pharmacological aspects of efficacy in the treatment of tobacco dependence." (PIOTR TUTKA, KATARZYNA MRÓZ WITOLD ZATOŃSKI) in pdf file format:


Cytyzyna – renesans znanego alkaloidu. Aspekty farmakologiczne zastosowania w leczeniu uzależnienia od nikotyny, PIOTR TUTKA, KATARZYNA MRÓZ WITOLD ZATOŃSKI,FARMAKOTERAPIA W PSYCHIATRII I NEUROLOGII, 2006, 1, 33–39




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The article "Cytisine – renaissance of well known alkaloid. Pharmacological aspects of efficacy in the treatment of tobacco dependence." in other languages
 
Cytyzyna – renesans znanego alkaloidu. Aspekty farmakologiczne zastosowania w leczeniu uzależnienia od nikotyny (PIOTR TUTKA, KATARZYNA MRÓZ WITOLD ZATOŃSKI) po Polsku:
Cytyzyna – renesans znanego alkaloidu. Aspekty farmakologiczne zastosowania w leczeniu uzależnienia od nikotyny
Katedra i Zakład Farmakologii i Toksykologii Akademii Medycznej w Lublinie, Zakład Epidemiologii i Prewencji Nowotworów, Centrum Onkologii – Instytut im. Marii Curie Skłodowskiej w Warszawie